Bruker Spatial Biology Blog

In this article: Summary Key Takeaways Best Practices and Key Learnings Summary: MicroRNAs can preserve useful biological information in challenging samples, including formalin-fixed paraffin-embedded brain tissue stored for decades. In…

Proteins are the functional unit of biology. Nearly 90% of FDA-approved drugs target them¹. Cell identity, immune phenotype, pathway activation, and disease state are defined at the protein level. And…

Authors: Kalyan Chavda, Lidan Wu, Aster Wardhani Spatial biology has entered the era of single-cell and subcellular resolution and generating high-dimensional molecular data is no longer the challenge. Interpreting it…

Authors: Kalyan Chavda, Christine Kang, Martin Shelton, Prajan Divakar As spatial biology transitions into a foundational tool in scientific research, Core Lab Managers and Principal Investigators are faced with an…

The ability to simultaneously map morphology, RNA, and protein at the subcellular level is the new frontier in cell biology. While the CosMx^® Spatial Molecular Imager (SMI) is renowned for…

With AGBT 2025 right around the corner and exciting announcements from Bruker Spatial Biology coming, we’re here to bring you the latest updates, innovations, and resources in spatial biology. Upcoming…

As spatial biology reshapes the future of biomedical research, spatial transcriptomics has emerged as one of the most powerful tools for revealing complex tissue biology. Technologies like the CosMx^® Spatial…

Tips to optimize the CosMx Multiomics sample prep for fragile tissues The CosMx multiomics platform enables sequential protein and RNA analysis on the same tissue sample, combining a 64-plex protein…

As multiomics becomes increasingly central to biological research and therapeutic development, scientists are seeking practical, scalable approaches to generate integrated datasets across molecular modalities. While single-cell multiomics and spatial multiomics…

This month brings exciting milestones across our portfolio. Washington University School of Medicine’s Orr Lab has been named a Bruker Spatial Biology Center of Excellence, marking a new chapter in…

Explore the CosMx SMI 2.0: Higher RNA sensitivity, whole transcriptome imaging, and faster high fidelity, subcellular spatial transcriptomics.

We're excited to share a major step forward: the nCounter^® platform is now enabling simplified RNA and protein analysis in a single workflow. Dive into our newest capabilities for bulk multiomics,…